Overview
Exquisitely designed for function, our hands enable a vast array and complexity of actions, bringing to life our experience of touch and making it possible to reshape our world around us. When brain or bodily injury impairs our ability to use our hands, their pivotal role in upholding our independence and quality of life is made painfully clear. My lab is dedicated to advancing our understanding of the neuroscience of human hand function for the purpose of harnessing this knowledge to improve patient rehabilitation.
Lab Web: https://sites.google.com/site/kfvalyear/
Additional Contact Information
Qualifications
- PhD: Neuroscience
Western University, Ontario, 2011 - BSc: Physiology and Psychology
Western University, Ontario, 2002
Teaching and Supervision
I teach rehabilitation neuroscience, brain stimulation, clinical and applied neuroscience, and methods in cognitive neuroscience. I supervise BSc, MSc and PhD student dissertations.
Research Interests
My lab is dedicated to advancing our understanding of the neuroscience of human hand function for the purpose of harnessing this knowledge to improve patient rehabilitation.
We use a wide array of methods, including functional MRI and brain stimulation.
Our current research targets two major clinical problems: (1) peripheral nerve injury, and (2) stroke.
Postgraduate Project Opportunities
Publications
2023
- PublishedTouch localization after nerve repair in the hand: Insights from a new measurement tool
Weber, M., Marshall, A., Timircan, R., McGlone, F., Watt, S., Onyekwelu, O., Booth, L., Jesudason, E., Lees, V. & Valyear, K. F., 1 Nov 2023, In: Journal of Neurophysiology. 130, 5, p. 1126-1141 16 p.
Research output: Contribution to journal › Article › peer-review
2022
- PublishedChanges in Primary Somatosensory Cortex Following Allogeneic Hand Transplantation or Autogenic Hand Replantation
Philip, B. A., Valyear, K. F., Cirstea, C. M., Baune, N. A., Kaufman, C. & Frey, S. H., 6 Oct 2022, In: Frontiers in neuroimaging. 1, 919694.
Research output: Contribution to journal › Article › peer-review - PublishedHand choice is unaffected by high frequency continuous theta burst transcranial magnetic stimulation to the posterior parietal cortex
Fitzpatrick, A. M., Dundon, N. M. & Valyear, K. F., 13 Oct 2022, In: PLoS ONE. 17, 10, e0275262.
Research output: Contribution to journal › Article › peer-review
2020
- PublishedInterhemispheric transfer of post-amputation cortical plasticity within the human somatosensory cortex
Valyear, K. F., Philip, B. A., Cirstea, C. M., Chen, P.-W., Baune, N., Marchal, N. & Frey, S. H., 1 Feb 2020, In: Neuroimage. 206, 116291.
Research output: Contribution to journal › Article › peer-review
2019
- PublishedActive haptic perception in robots: a review
Seminara, L., Gastaldo, P., Watt, S. J., Valyear, K. F., Zuher, F. & Mastrogiovanni, F., 17 Jul 2019, In: Frontiers in Neurorobotics. 13, 53.
Research output: Contribution to journal › Article › peer-review - PublishedGrasping with a new hand: Improved performance and normalized grasp-selective brain responses despite persistent functional changes in primary motor cortex and low-level sensory and motor impairments
Valyear, K. F., Mattos, D., Philip, B. A., Kaufman, C. & Frey, S. H., 15 Apr 2019, In: Neuroimage. 190, p. 275-288
Research output: Contribution to journal › Article › peer-review - PublishedNow and then: Hand choice is influenced by recent action history
Valyear, K. F., Fitzpatrick, A. M. & Dundon, N. M., Feb 2019, In: Psychonomic Bulletin and Review. 26, 1, p. 305-314 10 p.
Research output: Contribution to journal › Article › peer-review - PublishedPsychophysical and neuroimaging responses to moving stimuli in a patient with the Riddoch phenomenon due to bilateral visual cortex lesions
Arcaro, M. J., Thaler, L., Quinlan, D. J., Monaco, S., Khan, S., Valyear, K. F., Goebel, R., Dutton, G. N., Goodale, M. A., Kastner, S. & Culham, J. C., May 2019, In: Neuropsychologia. 128, May, p. 150-165 16 p.
Research output: Contribution to journal › Article › peer-review - PublishedThe neural basis of hand choice: An fMRI investigation of the Posterior Parietal Interhemispheric Competition model
Fitzpatrick, A. M., Dundon, N. M. & Valyear, K. F., 15 Jan 2019, In: Neuroimage. 185, p. 208-221 14 p.
Research output: Contribution to journal › Article › peer-review
2018
- PublishedRepresenting Visual Information in Motor Terms for Grasp Control
Valyear, K., Sept 2018, Reach-to-grasp behavior: Brain, Behavior and Modelling Across the Life Span. Corbetta, D. & Santello, M. (eds.). Routledge Taylor & Francis
Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
2017
- PublishedContributions of the parietal cortex to increased efficiency of planning-based action selection
Randerath, J., Valyear, K., Philip, B. A. & Frey, S. H., Oct 2017, In: Neuropsychologia. 105, October, p. 135-143
Research output: Contribution to journal › Article › peer-review
2016
- PublishedSensorimotor transformation: The hand that 'sees' to grasp
Valyear, K. F., 29 Jul 2016, In: Elife. 5, e18887.
Research output: Contribution to journal › Article › peer-review - PublishedThe Neuroscience of Human Tool Use
Valyear, K., 16 Dec 2016, Evolution of Nervous Systems: Second Edition. Kaas, J. (ed.). 2 ed. Oxford: Academic Press, p. 341-353 12 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
2015
- PublishedHand selection for object grasping is influenced by recent motor history
Valyear, K. F. & Frey, S. H., 2015, In: Psychonomic Bulletin and Review. 21, p. 566-573
Research output: Contribution to journal › Article › peer-review - PublishedHuman posterior parietal cortex mediates hand-specific planning
Valyear, K. F. & Frey, S. H., 2 Apr 2015, In: Neuroimage. 114, p. 226-238
Research output: Contribution to journal › Article › peer-review - PublishedTwo Routes to the Same Action: An Action Repetition Priming Study
Randerath, J., Valyear, K. F., Hood, A. & Frey, S. H., 2015, In: Journal of Motor Behavior. 47, 2, p. 142-152
Research output: Contribution to journal › Article › peer-review
2013
- PublishedDecoding the neural mechanisms of human tool use
Gallivan, J. P., McLean, D. A., Valyear, K. F. & Culham, J. C., 28 May 2013, In: Elife. 2, p. e00425
Research output: Contribution to journal › Article › peer-review
2012
- PublishedfMRI repetition suppression for familiar but not arbitrary actions with tools
Valyear, K. F., Gallivan, J. P., McLean, D. A. & Culham, J. C., 21 Mar 2012, In: Journal of Neuroscience. 32, 12, p. 4247-59 13 p.
Research output: Contribution to journal › Article › peer-review
2011
- PublishedDecoding action intentions from preparatory brain activity in human parieto-frontal networks
Gallivan, J. P., McLean, D. A., Valyear, K. F., Pettypiece, C. E. & Culham, J. C., 29 Jun 2011, In: Journal of Neuroscience. 31, 26, p. 9599-9610 12 p.
Research output: Contribution to journal › Article › peer-review - PublishedTo use or to move: goal-set modulates priming when grasping real tools
Valyear, K. F., Chapman, C. S., Gallivan, J. P., Mark, R. S. & Culham, J. C., Jul 2011, In: Experimental Brain Research. 212, 1, p. 125-42 18 p.
Research output: Contribution to journal › Article › peer-review
2010
- PublishedObserving learned object-specific functional grasps preferentially activates the ventral stream
Valyear, K. F. & Culham, J. C., May 2010, In: Journal of Cognitive Neurosience. 22, 5, p. 970-84 15 p.
Research output: Contribution to journal › Article › peer-review - PublishedfMRI activation during observation of others' reach errors
Malfait, N., Valyear, K. F., Culham, J. C., Anton, J.-L., Brown, L. E. & Gribble, P. L., Jul 2010, In: Journal of Cognitive Neurosience. 22, 7, p. 1493-1503 11 p.
Research output: Contribution to journal › Article › peer-review
2007
- PublishedDoes tool-related fMRI activity within the intraparietal sulcus reflect the plan to grasp?
Valyear, K. F., Cavina-Pratesi, C., Stiglick, A. J. & Culham, J. C., 31 Mar 2007, In: Neuroimage. 36 , Suppl 2, p. T94-T108
Research output: Contribution to journal › Article › peer-review - PublishedOrientation sensitivity to graspable objects: an fMRI adaptation study
Rice, N. J., Valyear, K. F., Goodale, M. A., Milner, A. D. & Culham, J. C., 31 Mar 2007, In: Neuroimage. 36 , Suppl 2, p. T87-93
Research output: Contribution to journal › Article › peer-review
2006
- PublishedA double dissociation between sensitivity to changes in object identity and object orientation in the ventral and dorsal visual streams: A human fMRI study
Valyear, K. F., Culham, J. C., Sharif, N., Westwood, D. & Goodale, M. A., Feb 2006, In: Neuropsychologia. 44, 2, p. 218-28 11 p.
Research output: Contribution to journal › Article › peer-review - PublishedDissociating arbitrary stimulus-response mapping from movement planning during preparatory period: evidence from event-related functional magnetic resonance imaging
Cavina-Pratesi, C., Valyear, K. F., Culham, J. C., Köhler, S., Obhi, S. S., Marzi, C. A. & Goodale, M. A., 1 Aug 2006, In: Journal of Neuroscience. 26, 10, p. 2704-13 10 p.
Research output: Contribution to journal › Article › peer-review - PublishedHuman parietal cortex in action
Culham, J. C. & Valyear, K. F., Apr 2006, In: Current Opinion in Neurobiology. 16, 2, p. 205-212 8 p.
Research output: Contribution to journal › Article › peer-review - PublishedThe fusiform face area is not sufficient for face recognition: evidence from a patient with dense prosopagnosia and no occipital face area
Steeves, J. K. E., Culham, J. C., Duchaine, B. C., Pratesi, C. C., Valyear, K. F., Schindler, I., Humphrey, G. K., Milner, A. D. & Goodale, M. A., 1 Apr 2006, In: Neuropsychologia. 44, 4, p. 594-609 16 p.
Research output: Contribution to journal › Article › peer-review - PublishedThe relationship between fMRI adaptation and repetition priming
Ganel, T., Gonzalez, C. L. R., Valyear, K. F., Culham, J. C., Goodale, M. A. & Köhler, S., Sept 2006, In: Neuroimage. 32, 3, p. 1432-1440 9 p.
Research output: Contribution to journal › Article › peer-review
2005
- PublishedNo evidence for visuomotor priming in a visually guided action task
Cant, J. S., Westwood, D. A., Valyear, K. F. & Goodale, M. A., 7 Jan 2005, In: Neuropsychologia. 43, 2, p. 216-26 11 p.
Research output: Contribution to journal › Article › peer-review - PublishedThe involvement of the "fusiform face area" in processing facial expression
Ganel, T., Valyear, K. F., Goshen-Gottstein, Y. & Goodale, M. A., 25 Feb 2005, In: Neuropsychologia. 43, 11, p. 1645-54 10 p.
Research output: Contribution to journal › Article › peer-review
2003
- PublishedPhotostimulation induces rapid growth of song-control brain regions in male and female chickadees (Poecile atricapilla)
MacDougall-Shackleton, S. A., Hernandez, A. M., Valyear, K. F. & Clark, A. P., 17 Apr 2003, In: Neuroscience Letters. 340, 3, p. 165-8 4 p.
Research output: Contribution to journal › Article › peer-review
Projects
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01/12/2019 – 30/07/2024 (Finished)
Layman's description
When a nerve of the hand is cut, the signalling between the hand and brain is disrupted, and as a consequence, the brain changes. These injuries are extremely common, with significant and longstanding personal and societal costs. Better understanding the links between brain changes and functional recovery holds promise for improving patient outcomes, and reducing these costs. This is the purpose of the proposed research. We will investigate the clinical significance of nerve-trauma-related brain changes in patients who have undergone surgical repairs of the nerve(s) of the hand. Using our established functional MRI and behavioural methods, we expect to identify brain changes in patients that predict poor sensory performance of the injured hand. This research will significantly advance our understanding of the functional consequences of brain changes following nerve damage to the hand, and set the stage for the development of new rehabilitation therapies designed to help reverse these changes.
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Improving child prostheses and rehabilitation of peripheral nerve injuries, using movement science
01/08/2019 – 01/08/2022 (Finished)
Description
This research aims to (i) develop upper-limb prostheses for young children that work better and are easier to use, and (ii) better understand the real-world consequences of peripheral nerve injury to the hand, and associated brain changes. This requires high-precision recording of natural hand movements. Support from the Welsh Government Ser Cymru III Enhancing Competitiveness Infrastructure Award was used to purchase a state-of-the-art motion-capture system to enable this research.
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Using paried-pulse TMS to investigate cortical mechanisms…
01/08/2015 – 01/08/2022 (Finished)
Links:
Other Grants and Projects
Research Grants
Welsh Government Ser Cymru III Enhancing Competitiveness Infrastructure Award
Improving child prostheses, and rehabilitation of peripheral nerve injuries, using movement science.
Principal Investigators: Ken Valyear; Simon Watt
March 2020
£64,472
Wellcome Trust Seed Award in Science (215186/Z/19/Z)
Mapping the consequences of peripheral nerve transection and repair on brain organisation and hand function.
Principal Investigator: Ken Valyear
December 2019 – May 2022
£94,063
Knowledge Exchange Skills Scholarships (KESS) II: PhD Studentship
The sensory and motor consequences of using an injured hand
Principal Investigators: Ken Valyear; Simon Watt; Edwin Jesudason
PhD candidate: Michela Paroli
June 2017 – 2020
£69300
Royal Society Research Grant (RG150098)
Specifying possible actions with objects: Paired-pulse TMS investigations of the underlying neural mechanisms
Principal Investigator: Ken Valyear
Co-investigator: Cosimo Urgesi
December 2015 – 2016
£15000