Qualifications
- PhD: Transcriptional regulation of the human surf-1/surf-2 promoter: Mutational analysis and serum stimulation (dept of Biochemistry)
University of Bristol, 1993–1998 - BSc: Applied Biological Sciences (Hons.) Upper second class.
University of the West of England, Bristol, 1990–1993 - Professional: HND Science
University of the West of England, Bristol, 1988–1990
Publications
2023
- PublishedCDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence
Crozier, L., Foy, R., adib, R., Kar, A., Holt, J., Pareri, A., Valverde, J., Riviera, R., Weston, W., Wilson, R., Regnault, C., Whitfield, P., Badonyi, M., Bennett, L., Vernon, E., Gamble, A., Marsh, J., Staples, C., Saurin, A., Barr, A. & Ly, T., 16 Nov 2023, In: Molecular Cell. 83, 22, p. 4062-4077 15 p.
Research output: Contribution to journal › Article › peer-review
2022
- PublishedTranslin facilitates RNA polymerase II dissociation and suppresses genome instability during RNase H2- and Dicer-deficiency
Gomez Escobar, N., Alsaiari, A., Alahmadi, H. A. S., Alzahrani, O., Vernon, E., Althagafi, H., Almobadel, N., Pryce, D., Wakeman, J. & Mcfarlane, R., 17 Jun 2022, In: PLOS Genetics. 18, 6, e1010267.
Research output: Contribution to journal › Article › peer-review
2020
- PublishedMRNIP is a replication fork protection factor
Bennett, L., Wilkie, A., Antonopoulou, E., Ceppi, I., Sanchez, A., Vernon, E., Gamble, A., Myers, K. N., Collis, S. J., Cejka, P. & Staples, C., 10 Jul 2020, In: Science Advances. 6, 28, 10 p., eaba5974.
Research output: Contribution to journal › Article › peer-review - PublishedMre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication
Böckemeier, L., Kraehenbuehl, R., Keszthelyi, A., Gasasira, M. U., Vernon, E., Beardmore, R., Broberg Vågbø, C., Chaplin, D., Collins, S., Krokan, H. E., Lambert, S. A. E., Paisz, B. & Hartsuiker, E., 29 May 2020, In: Science Advances. 6, 22, 9 p., eaaz4126.
Research output: Contribution to journal › Article › peer-review
2014
- PublishedIdentification of a class of human cancer germline genes with transcriptional silencing refractory to the hypomethylating drug 5-aza-2'-deoxycytidine
Almatrafi, A., Feichtinger, J., Vernon, E. G., Escobar, N. G., Wakeman, J. A., Larcombe, L. D. & McFarlane, R. J., 10 Nov 2014, In: Oncoscience. 1, 11, p. 745-750 6 p.
Research output: Contribution to journal › Article › peer-review
2007
- PublishedIGF-II and IGFBP-2 Differentially Regulate PTEN in Human Breast Cancer Cells
Perks, C., Vernon, E., Rosendahl, A., Tonge, D. & Holly, J., 30 Aug 2007, In: Oncogene. 26, 40, p. 5966-72 6 p.
Research output: Contribution to journal › Article › peer-review
2006
- PublishedInsulin-Like Growth Factor Binding Protein 3 Has Opposing Actions on Malignant and Nonmalignant Breast Epithelial Cells that Are Each Reversible and Dependent upon Cholesterol-Stabilized Integrin Receptor Complexes
Burrows, C., Laurence, J., Vernon, E., Carter, J., Clark, M., Mcintosh, J., McCaig, C., Winters, Z. & Perks, C., Aug 2006, In: Endocrinology. 147, 7, p. 3484-500 16 p.
Research output: Contribution to journal › Article › peer-review
2003
- PublishedThe parathyroid hormone-responsive B1 gene is interrupted by a t(1;7)(q42;p15) breakpoint associated with Wilms' tumour
Vernon, E., Malik, K., Reynolds, P., Powlesland, R., Dallosso, A., Jackson, S., Henthorn, K. & Brown, K. W., 5 Mar 2003, In: Oncogene. 22, p. 1371-80 9 p.
Research output: Contribution to journal › Article › peer-review
2002
- PublishedThrombocytopenia-absent radius syndrome: A clinical genetic study
Greenhalgh, K., Hotwell, R., Bottani, A., Ancliff, P., Brunner, H., Vershuuren-Bemelmans, C., Vernon, E., Brown, K. & Newbury-Ecob, R., Dec 2002, In: American Journal of Medical Genetics Part A. 39, 12, p. 876-81 5 p., DOI:.
Research output: Contribution to journal › Article › peer-review
2001
- PublishedGABAB receptors couple directly to the transcription factor ATF4
Vernon, E., Meyer, G., Pickard, L., Dev, K., Molnar, E., Collingridge, G. & Henley, J., Apr 2001, In: Molecular and Cellular Neuroscience. 17, 4, p. 637-45 9 p.
Research output: Contribution to journal › Article › peer-review
2000
- PublishedMyc and YY1 mediate activation of the Surf-1 promoter in response to serum growth factors
Vernon, E. & Gaston, K., 21 Jun 2000, In: Biochim. Biophys. Acta. 1492, 1, p. 172-9 7 p.
Research output: Contribution to journal › Article › peer-review
1997
- PublishedA functional YY1 binding site is necessary and sufficient to activate Surf-1 promoter activity in response to serum growth factors
Vernon, E. & Gaston, K., Oct 1997, In: Nucleic Acids Research. 25, 18, p. 3705-11 6 p.
Research output: Contribution to journal › Article › peer-review - PublishedSerum-dependent and cell cycle-dependent expression from a cytomegalovirus-based mammalian expression vector
Brightwell, G., Poirier, V., Vernon, E., Ivins, S. & Brown, K. W., Aug 1997, In: Gene. 194, 1, p. 115-23 8 p.
Research output: Contribution to journal › Article › peer-review