Publications
2023
- PublishedTau-mediated axonal degeneration is prevented by activation of the WldS pathway
Stubbs, K., Batchelor, B., Sivanantharajah, L., Sealey, M., Ramirez-Moreno, M., Ruiz, E., Richardson, B., Perry, V. H., Newman, T. A. & Mudher, A., Apr 2023, In: Brain Communications. 5, 2, fcad052.
Research output: Contribution to journal › Article › peer-review
2022
- PublishedCurcumin as a Holistic Treatment for Tau Pathology
Sivanantharajah, L. & Mudher, A., 19 May 2022, In: Frontiers in Pharmacology. 13, 903119.
Research output: Contribution to journal › Article › peer-review
2019
- PublishedAn evaluation of Drosophila as a model system for studying tauopathies such as Alzheimer's disease
Sivanantharajah, L., Mudher, A. & Shepherd, D., 1 May 2019, In: Journal of Neuroscience Methods. 319, May, p. 77-88 12 p.
Research output: Contribution to journal › Article › peer-review
2015
- PublishedCurrent techniques for high-resolution mapping of behavioral circuits in Drosophila
Sivanantharajah, L. & Zhang, B., Sept 2015, In: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology. 201, 9, p. 895-909 15 p.
Research output: Contribution to journal › Review article › peer-review - PublishedDifferential pleiotropy and HOX functional organization
Sivanantharajah, L. & Percival-Smith, A., 1 Feb 2015, In: Development Biology. 398, 1, p. 1-10 10 p.
Research output: Contribution to journal › Review article › peer-review
2014
- PublishedAcquisition of a Leucine Zipper Motif as a Mechanism of Antimorphy for an Allele of the Drosophila Hox Gene Sex Combs Reduced
Sivanantharajah, L. & Percival-Smith, A., 1 May 2014, In: G3: Genes, Genomes, Genetics. 4, 5, p. 829-838
Research output: Contribution to journal › Article › peer-review
2013
- PublishedDevelopmental competence and the induction of ectopic proboscises in Drosophila melanogaster
Percival-Smith, A., Sivanantharajah, L., Pelling, J. J. H. & Teft, W. A., Nov 2013, In: Development genes and evolution. 223, 6, p. 375-387 13 p.
Research output: Contribution to journal › Article › peer-review
2009
- PublishedAnalysis of the sequence and phenotype of Drosophila Sex combs reduced alleles reveals potential functions of conserved protein motifs of the Sex combs reduced protein
Sivanantharajah, L. & Percival-Smith, A., 1 May 2009, In: Genetics. 182, 1, p. 191-203 13 p.
Research output: Contribution to journal › Article › peer-review
Activities
2024
- Using the fruit fly for research @ Darganfod Discover 2024 (Wrexham's Science Festival)
Outreach event at which we will showcase the use of the fruit fly for research at the Association for the Study of Animal Behaviour (ASAB) booth at the Wrexam Science Festival.
4 Aug 2024
Activity: Types of Public engagement and outreach - Media article or participation (Contributor) - Southwest Fly Meeting at Bristol University
Talk entitled "Understanding the nature of selective neuronal vulnerability to tau-mediated toxicity"
26 Jun 2024
Links:
Activity: Oral presentation (Speaker) - Alzheimer's Research UK Research Conference
The UK’s largest dementia research conference taking place at the ACC in Liverpool Alzheimer’s Research UK Conference provides a fantastic chance to gain insights from colleagues working across basic, translational and clinical dementia research.
20 Mar 2024 – 21 Mar 2024
Links:
Activity: Participation in Academic conference (Speaker)
Projects
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Identifying molecular mechanisms in differential vulnerability of neurons to tau-mediated toxicity
01/06/2022 – 30/06/2026 (Active)
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HEFCW HEIR COVID extension to Charities bid (R35C40, F006505)
01/04/2021 – 31/10/2021 (Finished)
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Understanding the basis for selective vulnerability of differentneuronal populations
12/01/2017 – 31/07/2023 (Finished)