Prabhakar Srivastava is a Research Fellow at the Centre for Environmental Biotechnology (CEB) in the School of Environmental & Natural Sciences, Bangor University. Previously, he was a Postdoctoral Research Associate at Cardiff University with Prof. Rudolf K. Allemann and worked on “Engineering water capture mechanism in terpene synthases”, generating novel biocatalysts with potential in biotechnological applications. His present role in CEB focuses on the various aspects of Engineering microorganisms to degrade recalcitrant organic pollutants and enhance natural remediation processes.

• PhD: Biotechnology
  CSIR-National Chemical Laboratory, Pune, 2014
• MSc: Biotechnology
  Savitribai Phule Pune University, 2006

2024

• PublishedProduction of non-natural terpenoids through chemoenzymatic synthesis using substrate analogs
  Srivastava, P. L., Johnson, L. A., Miller, D. J. & Allemann, R. K., 24 Jun 2024, In: Methods in Enzymology. 699, p. 207-230 24 p.
  Research output: Contribution to journal › Article › peer-review
• PublishedSimulation-Guided Engineering Enables a Functional Switch in Selinadiene Synthase toward Hydroxylation
  Srivastava, P. L., Johns, S. T., Voice, A., Morley, K., Escorcia, A. M., Miller, D. J., Allemann, R. K. & van der Kamp, M. W., 19 Jul 2024, In: ACS Catalysis. 14, 14, p. 11034-11043 10 p.
  Research output: Contribution to journal › Article › peer-review
• PublishedSingle Point Mutation Abolishes Water Capture in Germacradien-4-ol Synthase
  González Requena, V., Srivastava, P. L., Miller, D. J. & Allemann, R. K., 2 Dec 2024, In: ChemBioChem. 25, 23, p. e202400290
  Research output: Contribution to journal › Article › peer-review

2023

• PublishedActive Site Loop Engineering Abolishes Water Capture in Hydroxylating Sesquiterpene Synthases
  Srivastava, P. L., Johns, S. T., Walters, R., Miller, D. J., Van der Kamp, M. W. & Allemann, R. K., 3 Nov 2023, In: ACS Catalysis. 13, 21, p. 14199-14204 6 p.
  Research output: Contribution to journal › Article › peer-review

2021

• PublishedGenome-wide discovery of OsHOX24-binding sites and regulation of desiccation stress response in rice
  Bhattacharjee, A., Srivastava, P. L., Nath, O. & Jain, M., 1 Jan 2021, In: Plant Molecular Biology. 105, 1-2, p. 205-214 10 p.
  Research output: Contribution to journal › Article › peer-review
• PublishedRedesigning the Molecular Choreography to Prevent Hydroxylation in Germacradien-11-ol Synthase Catalysis
  Srivastava, P. L., Escorcia, A. M., Huynh, F., Miller, D. J., Allemann, R. K. & van der Kamp, M. W., 5 Feb 2021, In: ACS Catalysis. 11, 3, p. 1033-1041 9 p.
  Research output: Contribution to journal › Article › peer-review

2020

• PublishedImmobilised Enzymes for Sesquiterpene Synthesis in Batch and Flow Systems
  Valikhani, D., Srivastava, P., Allemann, R. K. & Wirth, T., 20 Apr 2020, In: ChemCatChem. 12, 8
  Research output: Contribution to journal › Article › peer-review
• PublishedRecent Advances in Plant Nanobionics and Nanobiosensors for Toxicology Applications
  Ansari, M. H. D., Lavhale, S., Kalunke, R. M., Srivastava, P., Pandit, V., Gade, S., Yadav, S., Laux, P., Gemmati, D., Zamboni, P. & Singh, A. V., 1 Jan 2020, In: Current Nanoscience. 16, 1, p. 27-41
  Research output: Contribution to journal › Article › peer-review

2019

• PublishedTherapeutic potential of cyanobacterial pigment protein phycoerythrin: in silico and in vitro study of BACE1 interaction and in vivo Aβ reduction
  Chaubey, M. G., Patel, S. N., Rastogi, R. P., Srivastava, P. L., Singh, A. K., Madamwar, D. & Singh, N. K., 1 Aug 2019, In: International journal of biological macromolecules. 134, p. 368-378 11 p.
  Research output: Contribution to journal › Article › peer-review

2018

• PublishedComprehensive metabolic and transcriptomic profiling of various tissues provide insights for saponin biosynthesis in the medicinally important Asparagus racemosus
  Srivastava, P. L., Shukla, A. & Kalunke, R. M., 14 Jun 2018, In: Scientific Reports. 8, 1, p. 9098
  Research output: Contribution to journal › Article › peer-review
• PublishedRecent Highlights of RNA Sequencing Approaches for In-Depth Understanding of Plant Metabolic Engineering
  Srivastava, P., 24 Nov 2018, Recent Trends and Techniques in Plant Metabolic Engineering. Yadav, S. K., Kumar, V. & Singh, S. P. (eds.). Springer Singapore, p. 63-74 ( Recent Trends and Techniques in Plant Metabolic Engineering).
  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2016

• PublishedDe novo transcriptome assembly and comprehensive expression profiling in Crocus sativus to gain insights into apocarotenoid biosynthesis
  Jain, M., Srivastava, P. L., Verma, M., Ghangal, R. & Garg, R., 3 Mar 2016, In: Scientific Reports. 6, p. 22456
  Research output: Contribution to journal › Article › peer-review

2015

• PublishedCharacterization of 10-hydroxygeraniol dehydrogenase from Catharanthus roseus reveals cascaded enzymatic activity in iridoid biosynthesis
  Krithika, R., Srivastava, P. L., Rani, B., Kolet, S. P., Chopade, M., Soniya, M. & Thulasiram, H. V., 5 Feb 2015, In: Scientific Reports. 5, p. 8258
  Research output: Contribution to journal › Article › peer-review
• PublishedFunctional Characterization of Novel Sesquiterpene Synthases from Indian Sandalwood, Santalum album
  Srivastava, P. L., Daramwar, P. P., Krithika, R., Pandreka, A., Shankar, S. S. & Thulasiram, H. V., 15 May 2015, In: Scientific Reports. 5, p. 10095
  Research output: Contribution to journal › Article › peer-review

2014

• PublishedBiocatalyst mediated regio- and stereo-selective hydroxylation and epoxidation of (Z)-α-santalol
  Daramwar, P. P., Srivastava, P. L., Kolet, S. P. & Thulasiram, H. V., 21 Feb 2014, In: Organic and Biomolecular Chemistry. 12, 7, p. 1048-51 4 p.
  Research output: Contribution to journal › Article › peer-review

2013

• PublishedSelf-assembly to function: design, synthesis, and broad spectrum antimicrobial properties of short hybrid E-vinylogous lipopeptides
  Shankar, S. S., Benke, S. N., Nagendra, N., Srivastava, P. L., Thulasiram, H. V. & Gopi, H. N., 14 Nov 2013, In: Journal of Medicinal Chemistry. 56, 21, p. 8468-74 7 p.
  Research output: Contribution to journal › Article › peer-review

2012

• PublishedPreparative separation of α- and β-santalenes and (Z)-α- and (Z)-β-santalols using silver nitrate-impregnated silica gel medium pressure liquid chromatography and analysis of sandalwood oil
  Daramwar, P. P., Srivastava, P. L., Priyadarshini, B. & Thulasiram, H. V., 7 Oct 2012, In: Analyst. 137, 19, p. 4564-70 7 p.
  Research output: Contribution to journal › Article › peer-review