Jonathan has a BSc (Hons) in Biological Sciences (Physiology), and a PhD in Cardiovascular Physiology.  He teaches human, exercise and environmental physiology on sport and exercise science undergraduate and postgraduate degree programmes. Jonathan's research focuses primarily on understanding how blood pressure is regulated, and the importance this has for human circulatory control during exercise and other physiological stressors, such as high-altitude hypoxia.  

    

co-Dean of Research for the College of Medicine and Health 

Room G104, George Building, Normal Site

J.P.Moore@bangor.ac.uk

(01248) 383645

  • Other: Postgraduate certificate in teaching and learning in Higher Education, with Distinction
    University of Salford, 2000–2001
  • PhD: Responses to stimulation of coronary mechanoreceptors
    University of Leeds, 1991–1994
  • BSc: Biological Sciences (Physiology), second class, upper division (2:1)
    University of Edinburgh, 1986–1990

Teaching and Related Activity   

Teach and examine courses at:

Level 4: JXH1054  Human Physiology

Level 6: JXH3001  Research Project JXH3054 DIssertation,

Level 7: JXH4401 Performance Physiology, JXH4405 Research Project Proposal, JXH4406 Dissertation Proposal, 

Neural control and autonomic regulation of the heart and blood vessels. Having spent many years studying reflexes from vagal afferent nerve endings in the heart and pulmonary arteries, Jonathan is particularly interested in how these baroreceptors regulate sympathetic nervous system activity in health and disease.

Applications are encouraged from well-qualified students with a general interest in human, environmental and exercise physiology and/or a specific interest in neural regulation of the heart and blood vessels.

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  • PublishedCardiac Disease.
    Moore, J. P. & Porter, S. (Editor), 1 Jan 2008, Tidy's Physiotherapy: 14th Edition. 2008 ed. Churchill Livingstone, p. 212-240
    Research output: Chapter in Book/Report/Conference proceeding › Chapter

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2023

  • Sympathetic neural responses and adaptation to the challenge of exercise, and to high altitude stress

    Sympathetic nerves play a pivotal role in control of systemic vascular resistance and autonomic regulation of arterial blood pressure. Furthermore, microneurography, the technique for recording neural activity directly from peripheral nerves innervating skeletal muscle vessels, is a fundamental tool for studying sympathetic modulation of vascular resistance and blood pressure during a variety of physiological and environmental challenges. During a bout of vigorous exercise, increased muscle sympathetic nerve activity (MSNA) and ensuing vasoconstriction in contracting muscle avert a drop in arterial blood pressure and vital perfusion when metabolic vasodilation would otherwise threaten to outstrip the pumping capacity of the heart. Notably, increased sympathetic outflow to skeletal muscle vasculature during exercise arises from integration of multiple neural inputs to the lower brainstem, including central command, afferent feedback from contracting muscle, and the arterial baroreceptors. In healthy individuals, it is apparent that exercise training can lead to heightened basal MSNA and resetting of the vascular sympathetic baroreflex, adjustments that might be important for maintaining arterial blood pressure in the face of cardiac and vascular adaptation induced by years of athletic training. Exposure to high altitude (HA) hypoxia is another physiological state in which skeletal muscle vasodilation challenges sympathetic modulation of vascular resistance and arterial blood pressure. Although relatively few in number, microneurographic studies indicate that heightened MSNA is a feature of HA exposure, not only in lowland natives, but also in highland populations who have generational exposure to ambient hypoxia. This invited talk will explore mechanisms underpinning the sympathetic neural adaptive responses to exercise in health and compare these with alterations in sympathetic outflow that are a feature of altitude acclimatization and adaptation.

    10 Jul 2023

    Activity: Invited talk (Speaker)
  • Review Board Third National Centrifuge program

    Panel member and Reviewer

    Jun 2023

    Activity: Types of External academic engagement - Membership of peer review panel or committee (Contributor)
  • External Examiner PhD Thesis

    Mar 2023

    Activity: Examination (Examiner)

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